I am rebuilding my stack from source to incorporate this (primarily for ECH in nginx).
- Python 3.14.4's _ssl module breaks, there is a fix: https://github.com/python/cpython/pull/146217
- Git's IMAP support breaks, I just disabled it.
- PHP 8.5 breaks, a fix will be non-trivial
- python-cryptography breaks, in part because of a misguided OpenSSL version check